Chemical Profile and Structure
O - C(=O) - (CH2)9 - CH3 <-- Undecylenate Ester Chain (11 Carbons)
/
---CH---CH2
/ | \
CH2 CH CH2
| | |
C---C----CH
// |
CH CH2
\ /
CH=CH <-- Double Bond between Carbon 1 and 2
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- Chemical Name: 1,4-androstadien-3-one-17beta-ol
- Molecular Formula: C₃₀H₄₄O₃
- Base Compound: Testosterone (modified with a double bond at positions 1 and 2)
- Attached Ester: Undecylenate (11-carbon chain)
- Anabolic/Androgenic Ratio: 100:50 (compared to testosterone’s baseline ratio of 100:100)
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- Debilitation Recovery: Recommended as an aid for treating overworked, injured, or diseased horses to correct weight loss.
- Physical Condition: Improves overall musculature, vigor, and haircoat appearance during convalescence.
- Appetite Stimulation: Positively impacts nitrogen balance and noticeably stimulates appetite in undernourished animals.
Steroid Ester Lifetimes (Half-Life Comparison):
[Acetate] ■■■ 3 Days
[Cypionate] ■■■■■■■■■■ 8-12 Days
[Undecylenate] ■■■■■■■■■■■■■■ 14 Days
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- Elimination Half-Life: Approximately 14 days when administered via intramuscular injection.
- Detection Window: Because of the slow release and accumulation in fatty tissues, boldenone metabolites can be detected in urine for up to several months.
- Metabolic Pathway: Once released from the injection site, esterases cleave the undecylenate chain, liberating free boldenone to bind directly with cellular androgen receptors.
Mechanism of Action
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- Androgen Receptor Binding: It crosses cellular membranes to bind with the intracellular androgen receptor, initiating gene transcription that leads to increased cellular protein synthesis.
- Nitrogen Retention: It prevents muscle catabolism by maintaining a positive nitrogen balance in skeletal tissue.
- Erythropoietin (EPO) Stimulation: Boldenone strongly promotes the release of erythropoietin from the kidneys. This drastically raises red blood cell production (erythropoiesis), which increases blood oxygenation capacities.
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Human Misuse and Serious Health Risks
Regulatory and Anti-Doping Status
- World Anti-Doping Agency (WADA): Classified under Category S1.1 as an Anabolic Androgenic Steroid. It is banned at all times, both in-competition and out-of-competition.
- Athletic Safety: The USADA Athlete Guide on Boldenone warns that boldenone is one of the most common substances triggering positive anti-doping tests.
- Legal Classification: In the United States, it is classified as a Schedule III Controlled Substance under the Controlled Substances Act, making human possession or distribution without a specific prescription highly illegal.
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